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Announcements:

• Homework #5 (Lycan et al) is now online
• The Bio311 course schedule has been newly revised
• Be sure to pick up lab handouts in class today--these will cover week 7 and week 8 (this week and next)

Learning objectives for Monday 10/16/00:

Students should be able to…

1. Compare and constrast the following pairs of terms:

• IS elements and bacterial transposons
• Transposons and retrotransposons
• Viral and nonviral retrotransposons
• LINES and SINES

2. Describe evidence that would suggest that a given repetitive element is a transposon.

3. Describe how you could provide experimental evidence that a given mobile genetic element is a retrotransposon as opposed to a transposon.

4. Explain potential evolutionary advantages of having interspersed repetitive elements scattered throughout a genome. Include a discussion of gene duplication, exon shuffling, and rearrangement of enhancer sequences.

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