Treatments and Toxin Discovery
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The National Institutes of Health (NIH) has renewed Lewis & Clark’s grant in support of Associate Professor of Biology Greta Binford’s project, “Comparative venomes of recluse spiders and kin: treatments and toxin discovery.” Supported by the Academic Research Enhancement Award (AREA) program, this three-year multidisciplinary project will involve undergraduate students in cutting-edge bioinformatics-based research using proteomics and high throughput sequencing of transcriptomes. It will provide them with the opportunity to experience the power of applying integrative evolutionary approaches to issues of public health. The data collected will provide a comprehensive, comparative set of protein and peptide components in venoms of brown recluse spiders and their relatives. Comparative analyses will help decipher the mechanisms of evolutionary origin of venom toxins that cause dermonecrotic lesions. They will also inform risks associated with sicariid bites, and strategies for developing globally effective diagnostics and treatments. Discovery of lesser-known venom toxins will provide a platform for further investigation, including peptides with promise as pain modulators and antimicrobials. More about Dr. Binford’s work is available here.
April 2015
More Sponsored Projects and Research Compliance Office (SPARC) Stories
Sponsored Projects and Research Compliance is located in room 208 of Albany on the Undergraduate Campus.
MSC: 47
email sponsres@lclark.edu
voice 503-768-7211
SPARC uses a team email, so please email sponsres@lclark.edu
with questions or if we can be of assistance.
Assistant Vice President
Kelly L. DelFatti, CRA
503-768-7211
delfatti@lclark.edu
Research Administrator
Jessica Sweeney, MA
503-768-7193
jessicasweeney@lclark.edu
Sponsored Projects and Research Compliance
Lewis & Clark
615 S. Palatine Hill Road MSC 47
Portland OR 97219